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精液冷冻保存是实现优良种羊高效繁殖的关键技术，但冷冻—解冻过程会导致精子氧化损伤和膜结构破坏。传统冷冻保护剂存在渗透性差、靶向性弱和剂量毒性等问题，效果不尽人意。深入探讨了纳米材料在羊精液冷冻保存中的应用，研究表明:硒纳米颗粒能够提高羊精子冻后活力和抗氧化能力;氧化锌和金纳米颗粒有助于改善精液质量;纳米乳化剂可增强精子活力并减少氧化应激;草药提取物纳米颗粒可减轻精子氧化损伤;抗冻蛋白纳米颗粒能抑制冰晶生长，保护精子结构与功能纳米材料凭借其独特性能，在羊精液冷冻保存中展现出良好的应用潜力。
Abstract：Semen cryopreservation is a key technology for the efficient reproduction of excellent sheep breeds. However,the freeze-thaw process can lead to oxidative damage to sperm and destruction of membrane structure. Traditional cryoprotectants have problems such as poor permeability,weak targeting,and dose toxicity,resulting in unsatisfactory effects. This study delved into the application of nanomaterials in sheep semen cryopreservation. It was found that selenium nanoparticles can improve the post-thaw motility and antioxidant capacity of sheep sperm; zinc oxide and gold nanoparticles contribute to the improvement of semen quality; nanoemulsifiers can enhance sperm motility and reduce oxidative stress; herbal extract nanoparticles can alleviate oxidative damage to sperm; and antifreeze protein nanoparticles can inhibit ice crystal growth and protect the structure and function of sperm. In conclusion,with their unique properties,nanomaterials have demonstrated good application potential in sheep semen cryopreservation.
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基本信息:
DOI：10.19567/j.cnki.1008-0414.2025.11.003
中图分类号:S826.3;TB383.1
引用信息:
[1]刘文超,卢婕,连芳馨,等.纳米材料在羊精液冷冻保存中的研究应用进展[J].畜禽业,2025,36(11):12-17.DOI:10.19567/j.cnki.1008-0414.2025.11.003.
基金信息:
杨凌职业技术学院“博士+高职生”工作室建设项目(BG2023-007);杨凌职业技术学院院士工作室科研项目(YS2023-010);杨凌职业技术学院基金项目(0300111);杨凌职业技术学院大学生创新实践项目(CXSJ2025-010)
2025-11-18
2025-11-18